Publications

2025

Centromeric DNA amplification triggered by viral proteins activates nuclear cGAS
Xavier Lahaye, Patrick Tran Van, Camellia Chakraborty, Anna Shmakova, Ngoc Tran Bich Cao, Hermine Ferran, Ouardia Ait-Mohamed, Mathieu Maurin, Joshua J. Waterfall, Benedikt B. Kaufer, Patrick Fischer, Thomas Hennig, Lars Dölken, Patrick Lomonte, Daniele Fachinetti, Nicolas Manel
Cell. 2025
Human cytomegalovirus control in allogeneic stem cell transplant recipients in the letermovir era emerging humoral and cellular players
Chris D. Lauruschkat, Hannah Görge, Kerstin Knies, Benedikt Weißbrich, Lars Dölken, Carolin Köchel, Nina Imhof, Magdalena Huber, Hartmut Hengel, Hermann Einsele, Sebastian Wurster, Sabrina Kraus
Haematologica. 2025
Lässt sich der SARS-CoV-2-Infektionsstatus bei Kindern über pandemiebezogene Einstellungen und Sorgen ihrer Eltern vorhersagen? Daten der Würzburger Kindertagesstätten-Studien (Wü-KiTa-CoV, 2020–2022)
Thomas Jans, Maike Krauthausen, Carsten Bauer, Johannes Forster, Geraldine Engels, Franziska Pietsch, Julia Wallstabe, Victoria Rücker, Julia Wendel, Benedikt Weissbrich, Peter Heuschmann, Christoph Härtel, Lars Dölken, Oliver Kurzai, Ildikó Gágyor, Johannes G. Liese, Marcel Romanos, Andrea Streng
Das Gesundheitswesen. 2025
Unveiling immune interference: how the dendritic cell response to co-infection with Aspergillus fumigatus is modulated by human cytomegalovirus and its virokine CMV_IL-10
Linda Heilig, Lydia Bussemer, Lea Strobel, Kerstin Hünniger-Ast, Oliver Kurzai, Arnhild Grothey, Lars Dölken, Kerstin Laib Sampaio, Gianni Panagiotou, Alexander J. Westermann, Hermann Einsele, Sebastian Wurster, Sascha Schäuble, Jürgen Löffler
mBio. 2025
Host cell Z-RNAs activate ZBP1 during virus infections
Chaoran Yin, Aleksandr Fedorov, Hongyan Guo, Jeremy Chase Crawford, Claire Rousseau, Xiao Zhong, Riley M. Williams, Avishekh Gautam, Heather S. Koehler, Adam W. Whisnant, Thomas Hennig, Anna Rozina, Yuhan Zhong, Shuangjuan Lv, Valter Bergant, Shuqi Wang, Peter Dröge, Sven Miller, Maria Poptsova, Jan Rehwinkel, Andreas Pichlmair, Edward S. Mocarski, Paul G. Thomas, Lars Dölken, Ting Zhang, Alan Herbert, Siddharth Balachandran
Nature. 2025
A More Rapid Method for Culturing LUHMES-Derived Neurons Provides Greater Cell Numbers and Facilitates Studies of Multiple Viruses
Adam W. Whisnant, Stephanie E. Clark, José Alberto Aguilar-Briseño, Lorellin A. Durnell, Arnhild Grothey, Ann M. Miller, Steven M. Varga, Jeffery L. Meier, Charles Grose, Patrick L. Sinn, Jessica M. Tucker, Caroline C. Friedel, Wendy J. Maury, David H. Price, Lars Dölken
Viruses. 2025
High-Fidelity and Cost-Effective Engineering of SARS-CoV-2
Marco Olguin-Nava, Thomas Hennig, Charlene Börtlein, Patrick Bohn, Uddhav B. Ambi, Alexander Gabel, Lina M. Günter, Anne-Sophie Gribling-Burrer, Nora Schmidt, Neva Caliskan, Lars Dölken, Mathias Munschauer, Redmond P. Smyth
Viruses. 2025
HSV-1 infection induces a downstream shift of the +1 nucleosome
Elena Weiß, Adam W. Whisnant, Thomas Hennig, Lara Djakovic, Lars Dölken, Caroline C. Friedel
Journal of Virology. 2025

2024

Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells
Bibiana Costa, Jennifer Becker, Tobias Krammer, Felix Mulenge, Verónica Durán, Andreas Pavlou, Olivia Luise Gern, Xiaojing Chu, Yang Li, Luka Čičin-Šain, Britta Eiz-Vesper, Martin Messerle, Lars Dölken, Antoine-Emmanuel Saliba, Florian Erhard, Ulrich Kalinke
Nature Communications. 2024
Heterologous and homologous COVID-19 mRNA vaccination schemes for induction of basic immunity show similar immunogenicity regarding long-term spike-specific cellular immunity in healthcare workers
Isabell Wagenhäuser, Giovanni Almanzar, Franziska Bernhardine Förg, Astrid Stein, Isabella Eiter, Julia Reusch, Juliane Mees, Anna Herzog, Ulrich Vogel, Anna Frey, Thiên-Trí Lâm, Alexandra Schubert-Unkmeir, Lars Dölken, Oliver Kurzai, Stefan Frantz, Alexander Gabel, Nils Petri, Martina Prelog, Manuel Krone
Vaccine. 2024
Kontinuierliche Überwachung von SARS-CoV-2 Infektionen in Kindertagesstätten: eine qualitative Interviewstudie über die Erfahrungen von Betreuer*innen und Eltern mit verschiedenen Testverfahren im häuslichen Umfeld
Maike Krauthausen, David Gierszewski, Andrea Streng, Johannes Forster, Geraldine Engels, Franziska Pietsch, Julia Wallstabe, Thomas Jans, Viktoria Rücker, Marcel Romanos, Peter Heuschmann, Lars Dölken, Christoph Härtel, Oliver Kurzai, Johannes Liese, Ildikó Gágyor
Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen. 2024
SARS-CoV-2 antigen rapid detection tests: test performance during the COVID-19 pandemic and the impact of COVID-19 vaccination
Isabell Wagenhäuser, Kerstin Knies, Tamara Pscheidl, Michael Eisenmann, Sven Flemming, Nils Petri, Miriam McDonogh, Agmal Scherzad, Daniel Zeller, Anja Gesierich, Anna Katharina Seitz, Regina Taurines, Ralf-Ingo Ernestus, Johannes Forster, Dirk Weismann, Benedikt Weißbrich, Johannes Liese, Christoph Härtel, Oliver Kurzai, Lars Dölken, Alexander Gabel, Manuel Krone
eBioMedicine. 2024
Identification of novel canonical and cryptic HCMV-specific T-cell epitopes for HLA-A∗03 and HLA-B∗15 via peptide-PRISM
Alice Felicitas Rein, Chris David Lauruschkat, Ihsan Muchsin, Carolin Köchel, Sabine Tischer-Zimmermann, Liane Bauersfeld, Annika Nelde, Maren Lübke, Bhupesh Kumar Prusty, Andreas Schlosser, Anne Halenius, Britta Eiz-Vesper, Lars Dölken, Götz Ulrich Grigoleit, Hermann Einsele, Florian Erhard, Sabrina Kraus
Blood Advances. 2024
Impaired T cells and “memory-like” NK-cell reconstitution is linked to late-onset HCMV reactivation after letermovir cessation
Chris David Lauruschkat, Ihsan Muchsin, Alice Felicitas Rein, Florian Erhard, Denise Grathwohl, Lars Dölken, Carolin Köchel, Anne Nehmer, Christine Susanne Falk, Götz Ulrich Grigoleit, Hermann Einsele, Sebastian Wurster, Sabrina Kraus
Blood Advances. 2024
Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
Carolin Gerke, Liane Bauersfeld, Ivo Schirmeister, Chiara Noemi-Marie Mireisz, Valerie Oberhardt, Lea Mery, Di Wu, Christopher Sebastian Jürges, Robbert M Spaapen, Claudio Mussolino, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Lars Dölken, Wolfgang Paster, Florian Erhard, Maike Hofmann, Andreas Schlosser, Hartmut Hengel, Frank Momburg, Anne Halenius
eLife. 2024
Dynamic changes in the proximitome of neutral sphingomyelinase-2 (nSMase2) in TNFα stimulated Jurkat cells
Marie Schöl, Rebekka Schempp, Thomas Hennig, Dominik Wigger, Fabian Schumacher, Burkhard Kleuser, Christian Stigloher, Marco Van Ham, Lothar Jänsch, Sibylle Schneider-Schaulies, Lars Dölken, Elita Avota
Frontiers in Immunology. 2024
A clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI)
Carina R. Hartmann, Robin Khan, Jennifer Schöning, Maximilian Richter, Maike Willers, Sabine Pirr, Julia Heckmann, Johannes Dirks, Henner Morbach, Monika Konrad, Elena Fries, Magdalene Winkler, Johanna Büchel, Silvia Seidenspinner, Jonas Fischer, Claudia Vollmuth, Martin Meinhardt, Janina Marissen, Mirco Schmolke, Sibylle Haid, Thomas Pietschmann, Simone Backes, Lars Dölken, Ulrike Löber, Thomas Keil, Peter U. Heuschmann, Achim Wöckel, Sagar, Thomas Ulas, Sofia K. Forslund-Startceva, Christoph Härtel, Dorothee Viemann
Frontiers in Immunology. 2024
Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
Kevin Berg, Manivel Lodha, Isabel Delazer, Karolina Bartosik, Yilliam Cruz Garcia, Thomas Hennig, Elmar Wolf, Lars Dölken, Alexandra Lusser, Bhupesh K Prusty, Florian Erhard
Nucleic Acids Research. 2024
The relationship between mental health, sleep quality and the immunogenicity of COVID‐19 vaccinations
Isabell Wagenhäuser, Julia Reusch, Alexander Gabel, Juliane Mees, Helmut Nyawale, Anna Frey, Thiên‐Trí Lâm, Alexandra Schubert‐Unkmeir, Lars Dölken, Oliver Kurzai, Stefan Frantz, Nils Petri, Manuel Krone, Lukas B. Krone
Journal of Sleep Research. 2024
Herpes simplex virus 1 inhibits phosphorylation of RNA polymerase II CTD serine-7
Adam W. Whisnant, Oliver Dyck Dionisi, Valeria Salazar Sanchez, Julia M. Rappold, Lara Djakovic, Arnhild Grothey, Ana Luiza Marante, Patrick Fischer, Shitao Peng, Katharina Wolf, Thomas Hennig, Lars Dölken
Journal of Virology. 2024

2023

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9
Nora Schmidt, Sabina Ganskih, Yuanjie Wei, Alexander Gabel, Sebastian Zielinski, Hasmik Keshishian, Caleb A. Lareau, Liv Zimmermann, Jana Makroczyova, Cadence Pearce, Karsten Krey, Thomas Hennig, Sebastian Stegmaier, Lambert Moyon, Marc Horlacher, Simone Werner, Jens Aydin, Marco Olguin-Nava, Ramya Potabattula, Anuja Kibe, Lars Dölken, Redmond P. Smyth, Neva Caliskan, Annalisa Marsico, Christine Krempl, Jochen Bodem, Andreas Pichlmair, Steven A. Carr, Petr Chlanda, Florian Erhard, Mathias Munschauer
Cell. 2023
The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes
Lara Djakovic, Thomas Hennig, Katharina Reinisch, Andrea Milić, Adam W. Whisnant, Katharina Wolf, Elena Weiß, Tobias Haas, Arnhild Grothey, Christopher S. Jürges, Michael Kluge, Elmar Wolf, Florian Erhard, Caroline C. Friedel, Lars Dölken
Nature Communications. 2023
Virus variant–specific clinical performance of SARS coronavirus two rapid antigen tests in point-of-care use, from November 2020 to January 2022
Isabell Wagenhäuser, Kerstin Knies, Daniela Hofmann, Vera Rauschenberger, Michael Eisenmann, Julia Reusch, Alexander Gabel, Sven Flemming, Oliver Andres, Nils Petri, Max S. Topp, Michael Papsdorf, Miriam McDonogh, Raoul Verma-Führing, Agmal Scherzad, Daniel Zeller, Hartmut Böhm, Anja Gesierich, Anna K. Seitz, Michael Kiderlen, Micha Gawlik, Regina Taurines, Thomas Wurmb, Ralf-Ingo Ernestus, Johannes Forster, Dirk Weismann, Benedikt Weißbrich, Lars Dölken, Johannes Liese, Lars Kaderali, Oliver Kurzai, Ulrich Vogel, Manuel Krone
Clinical Microbiology and Infection. 2023
Clinical accuracy of SARS-CoV-2 rapid antigen testing in screening children and adolescents
Manuel Krone, Isabell Wagenhäuser, Kerstin Knies, Daniela Hofmann, Geraldine Engels, Regina Taurines, Miriam McDonogh, Sven Flemming, Thomas Meyer, Hartmut Böhm, Agmal Scherzad, Michael Eisenmann, Vera Rauschenberger, Alexander Gabel, Nils Petri, Julia Reusch, Johannes Forster, Benedikt Weißbrich, Lars Dölken, Oliver Kurzai, Ulrich Vogel, Christoph Härtel, Johannes Liese, Oliver Andres
Journal of Infection. 2023
Immunogenicity and safety of coadministration of COVID-19 and influenza vaccination
Isabell Wagenhäuser, Julia Reusch, Alexander Gabel, Anna Höhn, Thiên-Trí Lâm, Giovanni Almanzar, Martina Prelog, Lukas B. Krone, Anna Frey, Alexandra Schubert-Unkmeir, Lars Dölken, Stefan Frantz, Oliver Kurzai, Ulrich Vogel, Nils Petri, Manuel Krone
European Respiratory Journal. 2023
CD4+ T cells are the major predictor of HCMV control in allogeneic stem cell transplant recipients on letermovir prophylaxis
Chris David Lauruschkat, Ihsan Muchsin, Alice Rein, Florian Erhard, Denise Grathwohl, Lars Dölken, Carolin Köchel, Christine Susanne Falk, Hermann Einsele, Sebastian Wurster, Götz Ulrich Grigoleit, Sabrina Kraus
Frontiers in Immunology. 2023
Influencing factors of anti‐SARS‐CoV‐2‐spike‐IgG antibody titers in healthcare workers: A cross‐section study
Julia Reusch, Isabell Wagenhäuser, Alexander Gabel, Annika Eggestein, Anna Höhn, Thiên‐Trí Lâm, Anna Frey, Alexandra Schubert‐Unkmeir, Lars Dölken, Stefan Frantz, Oliver Kurzai, Ulrich Vogel, Manuel Krone, Nils Petri
Journal of Medical Virology. 2023
Decoding murine cytomegalovirus
Manivel Lodha, Ihsan Muchsin, Christopher Jürges, Vanda Juranic Lisnic, Anne L’Hernault, Andrzej J. Rutkowski, Bhupesh K. Prusty, Arnhild Grothey, Andrea Milic, Thomas Hennig, Stipan Jonjic, Caroline C. Friedel, Florian Erhard, Lars Dölken
PLOS Pathogens. 2023
Determinants of Influenza A infection rate in post-COVID-19 era
Isabell Wagenhäuser, Juliane Mees, Julia Reusch, Thiên-Trí Lâm, Alexandra Schubert-Unkmeir, Lukas B. Krone, Anna Frey, Oliver Kurzai, Stefan Frantz, Lars Dölken, Johannes Liese, Alexander Gabel, Nils Petri, Manuel Krone
Journal of Infection. 2023
Differential network interactions between psychosocial factors, mental health, and health-related quality of life in women and men
Martin Weiß, Marthe Gründahl, Jürgen Deckert, Felizitas A. Eichner, Mirjam Kohls, Stefan Störk, Peter U. Heuschmann, Grit Hein, the STAAB-COVID Study Group, Götz Gelbrich, Benedikt Weißbrich, Lars Dölken, Oliver Kurzai, Georg Ertl, Maria Barth, Caroline Morbach
Scientific Reports. 2023
The Cytomegalovirus M35 Protein Directly Binds to the Interferon-β Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes
Hella Schwanke, Vladimir Gonçalves Magalhães, Stefan Schmelz, Emanuel Wyler, Thomas Hennig, Thomas Günther, Adam Grundhoff, Lars Dölken, Markus Landthaler, Marco Van Ham, Lothar Jänsch, Konrad Büssow, Joop Van Den Heuvel, Wulf Blankenfeldt, Caroline C. Friedel, Florian Erhard, Melanie M. Brinkmann
Journal of Virology. 2023
HSV-1 Infection Induces a Downstream Shift of Promoter-Proximal Pausing for Host Genes
Elena Weiß, Thomas Hennig, Pilar Graßl, Lara Djakovic, Adam W. Whisnant, Christopher S. Jürges, Franziska Koller, Michael Kluge, Florian Erhard, Lars Dölken, Caroline C. Friedel
Journal of Virology. 2023
The Sensitivity of Rapid Tests for SARS-CoV-2 Antigen: Association With Clinical Manifestations, Viral Load, and Sublines
Kerstin Knies, Isabell Wagenhäuser, Daniela Hofmann, Vera Rauschenberger, Michael Eisenmann, Julia Reusch, Sven Flemming, Oliver Andres, Nils Petri, Max S. Topp, Michael Papsdorf, Miriam McDonogh, Raoul Verma-Führing, Agmal Scherzad, Daniel Zeller, Hartmut Böhm, Anja Gesierich, Anna Katharina Seitz, Michael Kiderlen, Micha Gawlik, Regina Taurines, Thomas Wurmb, Ralf-Ingo Ernestus, Johannes Forster, Dirk Weismann, Benedikt Weißbrich, Johannes Liese, Ulrich Vogel, Oliver Kurzai, Lars Dölken, Alexander Gabel, Manuel Krone
Deutsches Ärzteblatt International. 2023

2022

Selective inhibition of miRNA processing by a herpesvirus-encoded miRNA
Thomas Hennig, Archana B. Prusty, Benedikt B. Kaufer, Adam W. Whisnant, Manivel Lodha, Antje Enders, Julius Thomas, Francesca Kasimir, Arnhild Grothey, Teresa Klein, Stefanie Herb, Christopher Jürges, Markus Sauer, Utz Fischer, Thomas Rudel, Gunter Meister, Florian Erhard, Lars Dölken, Bhupesh K. Prusty
Nature. 2022
Time-resolved single-cell RNA-seq using metabolic RNA labelling
Florian Erhard, Antoine-Emmanuel Saliba, Alexandra Lusser, Christophe Toussaint, Thomas Hennig, Bhupesh K. Prusty, Daniel Kirschenbaum, Kathleen Abadie, Eric A. Miska, Caroline C. Friedel, Ido Amit, Ronald Micura, Lars Dölken
Nature Reviews Methods Primers. 2022
Acceptance of Different Self-sampling Methods for Semiweekly SARS-CoV-2 Testing in Asymptomatic Children and Childcare Workers at German Day Care Centers: A Nonrandomized Controlled Trial
Geraldine Engels, Johannes Forster, Andrea Streng, Viktoria Rücker, Paul Rudolph, Franziska Pietsch, Julia Wallstabe, Lars Wallstabe, Maike Krauthausen, Julia Schmidt, Timo Ludwig, Carsten Bauer, David Gierszewski, Jesper Bendig, Sandra Timme, Thomas Jans, Benedikt Weißbrich, Marcel Romanos, Lars Dölken, Peter Heuschmann, Christoph Härtel, Ildikó Gágyor, Marc Thilo Figge, Johannes Liese, Oliver Kurzai, Wue-KiTa-CoV 2.0-Study Group, Annsophie Amman, Anastasia Besenfelder, Leonie Bode, Inga Enders, Thiemo Frank, Kathrin Frei, Greta Habersack, Viktoria Hamway, Theresa Höferth, Thiên-Tri Lâm, Sabrina Mündlein, Konstanze Rauch, Christoph Schoen, Timo Spannagel, Fabian Rothbauer, Marianna Abert, Julia Bley, Tatjana Durnev, Carolin Glatzle, Antonia Hardung, Katharina Karch, Sebastian Kollert, Tanja Mastorakis, Lena Schregelmann, Victoria Sokalski, Eva-Lotta Tanzberger, Anne Thieme, Denise Yilmaz, Stefan Zimmerling, Pauline Nehm, Max Siegl, Brigitte Wehner, Kerstin Knies, Rebecca Richter, Hülya Düber, Monika Kraft, Christian Schuchardt, Barbara Finkenberg, Johann Löw
JAMA Network Open. 2022
The Hidden Enemy Within: Non-canonical Peptides in Virus-Induced Autoimmunity
Manivel Lodha, Florian Erhard, Lars Dölken, Bhupesh K. Prusty
Frontiers in Microbiology. 2022
Feasibility of SARS-CoV-2 Surveillance Testing Among Children and Childcare Workers at German Day Care Centers: A Nonrandomized Controlled Trial
Johannes Forster, Andrea Streng, Paul Rudolph, Viktoria Rücker, Julia Wallstabe, Sandra Timme, Franziska Pietsch, Katrin Hartmann, Maike Krauthausen, Julia Schmidt, Timo Ludwig, David Gierszewski, Thomas Jans, Geraldine Engels, Benedikt Weißbrich, Marcel Romanos, Lars Dölken, Peter Heuschmann, Christoph Härtel, Ildikó Gágyor, Marc Thilo Figge, Oliver Kurzai, Johannes Liese, Wü-KiTa-CoV Study Group, Anastasia Besenfelder, Lena Buechner, Kathrin Frei, Theresa Höferth, Thiên-Trí Lam, Sabrina Mündlein, Christoph Schoen, Alexandra Schubert-Unkmeir, Lars Wallstabe, Kerstin Knies, Rebecca Richter, Abdullah Almamy, Maxi Bettkober, Viktoria Engert, Phillipp Fecher, Jonas Fischer, Robin Khan, Fabian Kleindiek, Mirja Müller, Lara Müller-Scholden, Pauline Nehm, Jacobe Rapp, Christina Pfann, Maria Riedmeier, George Robinson, Sarah Schnee, Anna-Lena Sieg, Max Siegl, Fumi Sugihara, Anne Thieme, Gvantsa Uturgaidze, Brigitte Wehner
JAMA Network Open. 2022
Two murine cytomegalovirus microRNAs target the major viral immediate early 3 gene
Stefanie Herb, Jelena Zeleznjak, Thomas Hennig, Anne L’Hernault, Manivel Lodha, Christopher Jürges, Tihana Trsan, Vanda Juranic Lisnic, Stipan Jonjic, Florian Erhard, Astrid Krmpotic, Lars Dölken
Journal of General Virology. 2022
HSV-1 and influenza infection induce linear and circular splicing of the long NEAT1 isoform
Marie-Sophie Friedl, Lara Djakovic, Michael Kluge, Thomas Hennig, Adam W. Whisnant, Simone Backes, Lars Dölken, Caroline C. Friedel
PLOS ONE. 2022
pUL36 Deubiquitinase Activity Augments Both the Initiation and the Progression of Lytic Herpes Simplex Virus Infection in IFN-Primed Cells
Jonas Mohnke, Irmgard Stark, Mara Fischer, Patrick M. Fischer, Andreas Schlosser, Arnhild Grothey, Peter O’Hare, Beate Sodeik, Florian Erhard, Lars Dölken, Thomas Hennig
Journal of Virology. 2022
Critical Offset Magnetic PArticle SpectroScopy for rapid and highly sensitive medical point-of-care diagnostics
Patrick Vogel, Martin Andreas Rückert, Bernhard Friedrich, Rainer Tietze, Stefan Lyer, Thomas Kampf, Thomas Hennig, Lars Dölken, Christoph Alexiou, Volker Christian Behr
Nature Communications. 2022
Very Low Incidence of SARS-CoV-2, Influenza and RSV but High Incidence of Rhino-, Adeno- and Endemic Coronaviruses in Children With Acute Respiratory Infection in Primary Care Pediatric Practices During the Second and Third Wave of the SARS-CoV-2 Pandemic
Geraldine Engels, Johanna Sack, Benedikt Weissbrich, Katrin Hartmann, Kerstin Knies, Christoph Härtel, Andrea Streng, Lars Dölken, Johannes G. Liese, for the CoPraKid Study Group
Pediatric Infectious Disease Journal. 2022

2021

Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
Ashwin Narain, Pranjali Bhandare, Bikash Adhikari, Simone Backes, Martin Eilers, Lars Dölken, Andreas Schlosser, Florian Erhard, Apoorva Baluapuri, Elmar Wolf
Molecular Cell. 2021
Seroprävalenz von COVID-19 und psychosoziale Auswirkungen in der Allgemeinbevölkerung: Ergebnisse des STAAB-COVID-One Programms
Felizitas A Eichner, Götz Gelbrich, Benedikt Weißbrich, Lars Dölken, Oliver Kurzai, Jürgen Deckert, Georg Ertl, Maria Barth, Grit Hein, Hannelore Neuhauser, Caroline Morbach, Stefan Störk, Peter Heuschmann
Das Gesundheitswesen. 2021
A CMV seronegative donor to avoid T-cell inflation?
Hermann Einsele, Lars Dölken
Blood. 2021
Integrative transcription start site identification with iTiSS
Christopher S Jürges, Lars Dölken, Florian Erhard
Bioinformatics. 2021
SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro
Fengming Liu, Kun Han, Robert Blair, Kornelia Kenst, Zhongnan Qin, Berin Upcin, Philipp Wörsdörfer, Cecily C. Midkiff, Joseph Mudd, Elizaveta Belyaeva, Nicholas S. Milligan, Tyler D. Rorison, Nicole Wagner, Jochen Bodem, Lars Dölken, Bertal H. Aktas, Richard S. Vander Heide, Xiao-Ming Yin, Jay K. Kolls, Chad J. Roy, Jay Rappaport, Süleyman Ergün, Xuebin Qin
Frontiers in Cellular and Infection Microbiology. 2021
Dissecting Herpes Simplex Virus 1-Induced Host Shutoff at the RNA Level
Caroline C. Friedel, Adam W. Whisnant, Lara Djakovic, Andrzej J. Rutkowski, Marie-Sophie Friedl, Michael Kluge, James C. Williamson, Somesh Sai, Ramon Oliveira Vidal, Sascha Sauer, Thomas Hennig, Arnhild Grothey, Andrea Milić, Bhupesh K. Prusty, Paul J. Lehner, Nicholas J. Matheson, Florian Erhard, Lars Dölken
Journal of Virology. 2021
The Zinc Finger Antiviral Protein ZAP Restricts Human Cytomegalovirus and Selectively Binds and Destabilizes Viral UL4 / UL5 Transcripts
Ana Cristina Gonzalez-Perez, Markus Stempel, Emanuel Wyler, Christian Urban, Antonio Piras, Thomas Hennig, Sabina Ganskih, Yuanjie Wei, Albert Heim, Markus Landthaler, Andreas Pichlmair, Lars Dölken, Mathias Munschauer, Florian Erhard, Melanie M. Brinkmann
mBio. 2021
Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation
Xiuye Wang, Liang Liu, Adam W. Whisnant, Thomas Hennig, Lara Djakovic, Nabila Haque, Cindy Bach, Rozanne M. Sandri-Goldin, Florian Erhard, Caroline C. Friedel, Lars Dölken, Yongsheng Shi
PLOS Genetics. 2021
Concatemeric Broccoli reduces mRNA stability and induces aggregates
Marco R. Rink, Marisa A. P. Baptista, Felix J. Flomm, Thomas Hennig, Adam W. Whisnant, Natalia Wolf, Jürgen Seibel, Lars Dölken, Jens B. Bosse
PLOS ONE. 2021
Performance of Three SARS-CoV-2 Immunoassays, Three Rapid Lateral Flow Tests, and a Novel Bead-Based Affinity Surrogate Test for the Detection of SARS-CoV-2 Antibodies in Human Serum
Manuel Krone, Julia Gütling, Johannes Wagener, Thiên-Trí Lâm, Christoph Schoen, Ulrich Vogel, August Stich, Florian Wedekink, Jörg Wischhusen, Thomas Kerkau, Niklas Beyersdorf, Silvana Klingler, Simone Backes, Lars Dölken, Georg Gasteiger, Oliver Kurzai, Alexandra Schubert-Unkmeir
Journal of Clinical Microbiology. 2021
Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility
Jelena Tomac, Marija Mazor, Berislav Lisnić, Mijo Golemac, Daria Kveštak, Marina Bralić, Lidija Bilić Zulle, Melanie M. Brinkmann, Lars Dölken, Line S. Reinert, Soren R. Paludan, Astrid Krmpotić, Stipan Jonjić, Vanda Juranić Lisnić
Immunity. 2021
Clinical performance evaluation of SARS-CoV-2 rapid antigen testing in point of care usage in comparison to RT-qPCR
Isabell Wagenhäuser, Kerstin Knies, Vera Rauschenberger, Michael Eisenmann, Miriam McDonogh, Nils Petri, Oliver Andres, Sven Flemming, Micha Gawlik, Michael Papsdorf, Regina Taurines, Hartmut Böhm, Johannes Forster, Dirk Weismann, Benedikt Weißbrich, Lars Dölken, Johannes Liese, Oliver Kurzai, Ulrich Vogel, Manuel Krone
eBioMedicine. 2021
ITN—VIROINF: Understanding (Harmful) Virus-Host Interactions by Linking Virology and Bioinformatics
Winfried Goettsch, Niko Beerenwinkel, Li Deng, Lars Dölken, Bas E. Dutilh, Florian Erhard, Lars Kaderali, Max Von Kleist, Roland Marquet, Jelle Matthijnssens, Shawna McCallin, Dino McMahon, Thomas Rattei, Ronald P. Van Rij, David L. Robertson, Martin Schwemmle, Noam Stern-Ginossar, Manja Marz
Viruses. 2021
Remdesivir for Early COVID-19 Treatment of High-Risk Individuals Prior to or at Early Disease Onset—Lessons Learned
Lars Dölken, August Stich, Christoph D. Spinner
Viruses. 2021
A Review of the Multipronged Attack of Herpes Simplex Virus 1 on the Host Transcriptional Machinery
Thomas Hennig, Lara Djakovic, Lars Dölken, Adam W. Whisnant
Viruses. 2021

2020

Herpes simplex virus blocks host transcription termination via the bimodal activities of ICP27
Xiuye Wang, Thomas Hennig, Adam W. Whisnant, Florian Erhard, Bhupesh K. Prusty, Caroline C. Friedel, Elmira Forouzmand, William Hu, Luke Erber, Yue Chen, Rozanne M. Sandri-Goldin, Lars Dölken, Yongsheng Shi
Nature Communications. 2020
Integrative functional genomics decodes herpes simplex virus 1
Adam W. Whisnant, Christopher S. Jürges, Thomas Hennig, Emanuel Wyler, Bhupesh Prusty, Andrzej J. Rutkowski, Anne L’hernault, Lara Djakovic, Margarete Göbel, Kristina Döring, Jennifer Menegatti, Robin Antrobus, Nicholas J. Matheson, Florian W. H. Künzig, Guido Mastrobuoni, Chris Bielow, Stefan Kempa, Chunguang Liang, Thomas Dandekar, Ralf Zimmer, Markus Landthaler, Friedrich Grässer, Paul J. Lehner, Caroline C. Friedel, Florian Erhard, Lars Dölken
Nature Communications. 2020
Identification of the Cryptic HLA-I Immunopeptidome
Florian Erhard, Lars Dölken, Bastian Schilling, Andreas Schlosser
Cancer Immunology Research. 2020
Biodistribution and serologic response in SARS-CoV-2 induced ARDS: A cohort study
Tobias Schlesinger, Benedikt Weißbrich, Florian Wedekink, Quirin Notz, Johannes Herrmann, Manuel Krone, Magdalena Sitter, Benedikt Schmid, Markus Kredel, Jan Stumpner, Lars Dölken, Jörg Wischhusen, Peter Kranke, Patrick Meybohm, Christopher Lotz
PLOS ONE. 2020
The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment
Henrik Einwächter, Alexander Heiseke, Andreas Schlitzer, Georg Gasteiger, Heiko Adler, David Voehringer, Markus G. Manz, Zsolt Ruzsics, Lars Dölken, Ulrich H. Koszinowski, Tim Sparwasser, Wolfgang Reindl, Stefan Jordan
Frontiers in Immunology. 2020
The SARS-CoV-2 RNA–protein interactome in infected human cells
Nora Schmidt, Caleb A. Lareau, Hasmik Keshishian, Sabina Ganskih, Cornelius Schneider, Thomas Hennig, Randy Melanson, Simone Werner, Yuanjie Wei, Matthias Zimmer, Jens Ade, Luisa Kirschner, Sebastian Zielinski, Lars Dölken, Eric S. Lander, Neva Caliskan, Utz Fischer, Jörg Vogel, Steven A. Carr, Jochen Bodem, Mathias Munschauer
Nature Microbiology. 2020

2019

scSLAM-seq reveals core features of transcription dynamics in single cells
Florian Erhard, Marisa A. P. Baptista, Tobias Krammer, Thomas Hennig, Marius Lange, Panagiota Arampatzi, Christopher S. Jürges, Fabian J. Theis, Antoine-Emmanuel Saliba, Lars Dölken
Nature. 2019
P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress
Andrii Bugai, Alexandre J.C. Quaresma, Caroline C. Friedel, Tina Lenasi, Robert Düster, Christopher R. Sibley, Koh Fujinaga, Petra Kukanja, Thomas Hennig, Melanie Blasius, Matthias Geyer, Jernej Ule, Lars Dölken, Matjaž Barborič
Molecular Cell. 2019
Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis
Charlene Börtlein, Fabian Schumacher, Burkhard Kleuser, Lars Dölken, Elita Avota
Frontiers in Cell and Developmental Biology. 2019
The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors
Jelena Železnjak, Vanda Juranić Lisnić, Branka Popović, Berislav Lisnić, Marina Babić, Anne Halenius, Anne L’Hernault, Tihana Lenac Roviš, Hartmut Hengel, Florian Erhard, Alec J. Redwood, Silvia M. Vidal, Lars Dölken, Astrid Krmpotić, Stipan Jonjić
Journal of Experimental Medicine. 2019
Piscine Orthoreovirus 3 Is Not the Causative Pathogen of Proliferative Darkening Syndrome (PDS) of Brown Trout (Salmo trutta fario)
Robert Fux, Daniela Arndt, Martin C. Langenmayer, Julia Schwaiger, Hermann Ferling, Nicole Fischer, Daniela Indenbirken, Adam Grundhoff, Lars Dölken, Mikolaj Adamek, Dieter Steinhagen, Gerd Sutter
Viruses. 2019

2018

Improved Ribo-seq enables identification of cryptic translation events
Florian Erhard, Anne Halenius, Cosima Zimmermann, Anne L’Hernault, Daniel J Kowalewski, Michael P Weekes, Stefan Stevanovic, Ralf Zimmer, Lars Dölken
Nature Methods. 2018
Dissecting newly transcribed and old RNA using GRAND-SLAM
Christopher Jürges, Lars Dölken, Florian Erhard
Bioinformatics. 2018
HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes
Thomas Hennig, Marco Michalski, Andrzej J. Rutkowski, Lara Djakovic, Adam W. Whisnant, Marie-Sophie Friedl, Bhaskar Anand Jha, Marisa A. P. Baptista, Anne L’Hernault, Florian Erhard, Lars Dölken, Caroline C. Friedel
PLOS Pathogens. 2018
RNA dynamics revealed by metabolic RNA labeling and biochemical nucleoside conversions
Marisa A P Baptista, Lars Dölken
Nature Methods. 2018

2017

Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection
Emanuel Wyler, Jennifer Menegatti, Vedran Franke, Christine Kocks, Anastasiya Boltengagen, Thomas Hennig, Kathrin Theil, Andrzej Rutkowski, Carmelo Ferrai, Laura Baer, Lisa Kermas, Caroline Friedel, Nikolaus Rajewsky, Altuna Akalin, Lars Dölken, Friedrich Grässer, Markus Landthaler
Genome Biology. 2017
High-Resolution Gene Expression Profiling of RNA Synthesis, Processing, and Decay by Metabolic Labeling of Newly Transcribed RNA Using 4-Thiouridine
Andrzej J. Rutkowski, Lars Dölken
Eukaryotic Transcriptional and Post-Transcriptional Gene Expression Regulation. 2017

2016

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway
Kevin A. Robertson, Wei Yuan Hsieh, Thorsten Forster, Mathieu Blanc, Hongjin Lu, Peter J. Crick, Eylan Yutuc, Steven Watterson, Kimberly Martin, Samantha J. Griffiths, Anton J. Enright, Mami Yamamoto, Madapura M. Pradeepa, Kimberly A. Lennox, Mark A. Behlke, Simon Talbot, Jürgen Haas, Lars Dölken, William J. Griffiths, Yuqin Wang, Ana Angulo, Peter Ghazal
PLOS Biology. 2016
Effects of Prednisolone on Disease Progression in Antiretroviral-Untreated HIV Infection: A 2-Year Randomized, Double-Blind Placebo-Controlled Clinical Trial
Christa Kasang, Samuel Kalluvya, Charles Majinge, Gilbert Kongola, Mathias Mlewa, Irene Massawe, Rogatus Kabyemera, Kinanga Magambo, Albrecht Ulmer, Hartwig Klinker, Eva Gschmack, Anne Horn, Eleni Koutsilieri, Wolfgang Preiser, Daniela Hofmann, Johannes Hain, Andreas Müller, Lars Dölken, Benedikt Weissbrich, Axel Rethwilm, August Stich, Carsten Scheller
PLOS ONE. 2016

2015

Widespread disruption of host transcription termination in HSV-1 infection
Andrzej J. Rutkowski, Florian Erhard, Anne L’Hernault, Thomas Bonfert, Markus Schilhabel, Colin Crump, Philip Rosenstiel, Stacey Efstathiou, Ralf Zimmer, Caroline C. Friedel, Lars Dölken
Nature Communications. 2015
Small RNAs growing tall: miRNAs as drug targets in herpesvirus infections
Anne L’Hernault, Lars Dölken
Current Opinion in Virology. 2015
Lymph Node Macrophages Restrict Murine Cytomegalovirus Dissemination
Helen E. Farrell, Nick Davis-Poynter, Kimberley Bruce, Clara Lawler, Lars Dolken, Michael Mach, Philip G. Stevenson
Journal of Virology. 2015
RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway
Yasuhiro Murakawa, Michael Hinz, Janina Mothes, Anja Schuetz, Michael Uhl, Emanuel Wyler, Tomoharu Yasuda, Guido Mastrobuoni, Caroline C. Friedel, Lars Dölken, Stefan Kempa, Marc Schmidt-Supprian, Nils Blüthgen, Rolf Backofen, Udo Heinemann, Jana Wolf, Claus Scheidereit, Markus Landthaler
Nature Communications. 2015

2014

Reversible Silencing of Cytomegalovirus Genomes by Type I Interferon Governs Virus Latency
Franziska Dağ, Lars Dölken, Julia Holzki, Anja Drabig, Adrien Weingärtner, Johannes Schwerk, Stefan Lienenklaus, Ianina Conte, Robert Geffers, Colin Davenport, Ulfert Rand, Mario Köster, Siegfried Weiß, Barbara Adler, Dagmar Wirth, Martin Messerle, Hansjörg Hauser, Luka Čičin-Šain
PLoS Pathogens. 2014
Widespread context dependency of microRNA-mediated regulation
Florian Erhard, Jürgen Haas, Diana Lieber, Georg Malterer, Lukasz Jaskiewicz, Mihaela Zavolan, Lars Dölken, Ralf Zimmer
Genome Research. 2014
Murine Cytomegalovirus Virion-Associated Protein M45 Mediates Rapid NF-κB Activation after Infection
Eva Krause, Miranda De Graaf, Patricia M. Fliss, Lars Dölken, Wolfram Brune
Journal of Virology. 2014

2013

CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response
Joanna Bancerek, Zachary C. Poss, Iris Steinparzer, Vitaly Sedlyarov, Thaddäus Pfaffenwimmer, Ivana Mikulic, Lars Dölken, Birgit Strobl, Mathias Müller, Dylan J. Taatjes, Pavel Kovarik
Immunity. 2013
Natural Killer Cells Are Required for Extramedullary Hematopoiesis following Murine Cytomegalovirus Infection
Stefan Jordan, Zsolt Ruzsics, Maja Mitrović, Thomas Baranek, Jurica Arapović, Astrid Krmpotić, Eric Vivier, Marc Dalod, Stipan Jonjić, Lars Dölken, Ulrich H. Koszinowski
Cell Host & Microbe. 2013
4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response
Kaspar Burger, Bastian Mühl, Markus Kellner, Michaela Rohrmoser, Anita Gruber-Eber, Lukas Windhager, Caroline C Friedel, Lars Dölken, Dirk Eick
RNA Biology. 2013
RIP-chip enrichment analysis
Florian Erhard, Lars Dölken, Ralf Zimmer
Bioinformatics. 2013
Nontransformed, GM-CSF–dependent macrophage lines are a unique model to study tissue macrophage functions
György Fejer, Mareike Dorothee Wegner, Ildiko Györy, Idan Cohen, Peggy Engelhard, Elena Voronov, Thomas Manke, Zsolt Ruzsics, Lars Dölken, Olivia Prazeres Da Costa, Nora Branzk, Michael Huber, Antje Prasse, Robert Schneider, Ron N. Apte, Chris Galanos, Marina A. Freudenberg
Proceedings of the National Academy of Sciences. 2013
Inactivation of Intergenic Enhancers by EBNA3A Initiates and Maintains Polycomb Signatures across a Chromatin Domain Encoding CXCL10 and CXCL9
Marie L. Harth-Hertle, Barbara A. Scholz, Florian Erhard, Laura V. Glaser, Lars Dölken, Ralf Zimmer, Bettina Kempkes
PLoS Pathogens. 2013
PARma: identification of microRNA target sites in AGO-PAR-CLIP data
Florian Erhard, Lars Dölken, Lukasz Jaskiewicz, Ralf Zimmer
Genome Biology. 2013
Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis
Mirko Trilling, Nicolás Bellora, Andrzej J. Rutkowski, Miranda De Graaf, Paul Dickinson, Kevin Robertson, Olivia Prazeres Da Costa, Peter Ghazal, Caroline C. Friedel, M. Mar Albà, Lars Dölken
Nucleic Acids Research. 2013
Metabolic Labeling of Newly Transcribed RNA for High Resolution Gene Expression Profiling of RNA Synthesis, Processing and Decay in Cell Culture
Bernd Rädle, Andrzej J. Rutkowski, Zsolt Ruzsics, Caroline C. Friedel, Ulrich H. Koszinowski, Lars Dölken
Journal of Visualized Experiments. 2013
Genome-wide survey of interindividual differences of RNA stability in human lymphoblastoid cell lines
Jubao Duan, Jianxin Shi, Xijin Ge, Lars Dölken, Winton Moy, Deli He, Sandra Shi, Alan R. Sanders, Jeff Ross, Pablo V. Gejman
Scientific Reports. 2013
High Resolution Gene Expression Profiling of RNA Synthesis, Processing, and Decay by Metabolic Labeling of Newly Transcribed RNA Using 4-Thiouridine
Lars Dölken
Virus-Host Interactions: Methods and Protocols. 2013

2012

Real-time Transcriptional Profiling of Cellular and Viral Gene Expression during Lytic Cytomegalovirus Infection
Lisa Marcinowski, Michael Lidschreiber, Lukas Windhager, Martina Rieder, Jens B. Bosse, Bernd Rädle, Thomas Bonfert, Ildiko Györy, Miranda De Graaf, Olivia Prazeres Da Costa, Philip Rosenstiel, Caroline C. Friedel, Ralf Zimmer, Zsolt Ruzsics, Lars Dölken
PLoS Pathogens. 2012
Degradation of Cellular miR-27 by a Novel, Highly Abundant Viral Transcript Is Important for Efficient Virus Replication In Vivo
Lisa Marcinowski, Mélanie Tanguy, Astrid Krmpotic, Bernd Rädle, Vanda J. Lisnić, Lee Tuddenham, Béatrice Chane-Woon-Ming, Zsolt Ruzsics, Florian Erhard, Corinna Benkartek, Marina Babic, Ralf Zimmer, Joanne Trgovcich, Ulrich H. Koszinowski, Stipan Jonjic, Sébastien Pfeffer, Lars Dölken
PLoS Pathogens. 2012
Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution
Lukas Windhager, Thomas Bonfert, Kaspar Burger, Zsolt Ruzsics, Stefan Krebs, Stefanie Kaufmann, Georg Malterer, Anne L’Hernault, Markus Schilhabel, Stefan Schreiber, Philip Rosenstiel, Ralf Zimmer, Dirk Eick, Caroline C. Friedel, Lars Dölken
Genome Research. 2012
Small RNA Deep Sequencing Identifies MicroRNAs and Other Small Noncoding RNAs from Human Herpesvirus 6B
Lee Tuddenham, Jette S. Jung, Béatrice Chane-Woon-Ming, Lars Dölken, Sébastien Pfeffer
Journal of Virology. 2012

2011

Shedding Light on the Elusive Role of Endothelial Cells in Cytomegalovirus Dissemination
Torsten Sacher, Joachim Andrassy, Aivars Kalnins, Lars Dölken, Stefan Jordan, Jürgen Podlech, Zsolt Ruzsics, Karl-Walter Jauch, Matthias J. Reddehase, Ulrich H. Koszinowski
PLoS Pathogens. 2011
Human Cytomegalovirus Disrupts the Major Histocompatibility Complex Class I Peptide-Loading Complex and Inhibits Tapasin Gene Transcription
Anne Halenius, Sebastian Hauka, Lars Dölken, Jan Stindt, Henrike Reinhard, Constanze Wiek, Helmut Hanenberg, Ulrich H. Koszinowski, Frank Momburg, Hartmut Hengel
Journal of Virology. 2011
Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast
Christian Miller, Björn Schwalb, Kerstin Maier, Daniel Schulz, Sebastian Dümcke, Benedikt Zacher, Andreas Mayer, Jasmin Sydow, Lisa Marcinowski, Lars Dölken, Dietmar E Martin, Achim Tresch, Patrick Cramer
Molecular Systems Biology. 2011
Synthesis and decay of varicella zoster virus transcripts
Yevgeniy Azarkh, Lars Dölken, Maria Nagel, Don Gilden, Randall J. Cohrs
Journal of NeuroVirology. 2011
The miRNA-targetome of KSHV and EBV in human B-cells
Georg Malterer, Lars Dölken, Jürgen Haas
RNA Biology. 2011

2010

Systematic Analysis of Viral and Cellular MicroRNA Targets in Cells Latently Infected with Human γ-Herpesviruses by RISC Immunoprecipitation Assay
Lars Dölken, Georg Malterer, Florian Erhard, Sheila Kothe, Caroline C. Friedel, Guillaume Suffert, Lisa Marcinowski, Natalie Motsch, Stephanie Barth, Michaela Beitzinger, Diana Lieber, Susanne M. Bailer, Reinhard Hoffmann, Zsolt Ruzsics, Elisabeth Kremmer, Sébastien Pfeffer, Ralf Zimmer, Ulrich H. Koszinowski, Friedrich Grässer, Gunter Meister, Jürgen Haas
Cell Host & Microbe. 2010
HALO—a Java framework for precise transcript half-life determination
Caroline C. Friedel, Stefanie Kaufmann, Lars Dölken, Ralf Zimmer
Bioinformatics. 2010
Cytomegalovirus microRNAs Facilitate Persistent Virus Infection in Salivary Glands
Lars Dölken, Astrid Krmpotic, Sheila Kothe, Lee Tuddenham, Mélanie Tanguy, Lisa Marcinowski, Zsolt Ruzsics, Naama Elefant, Yael Altuvia, Hanah Margalit, Ulrich H. Koszinowski, Stipan Jonjic, Sébastien Pfeffer
PLoS Pathogens. 2010
A Spread-Deficient Cytomegalovirus for Assessment of First-Target Cells in Vaccination
Christian Andreas Mohr, Jurica Arapovic, Hermine Mühlbach, Marc Panzer, Annelies Weyn, Lars Dölken, Astrid Krmpotic, David Voehringer, Zsolt Ruzsics, Ulrich Koszinowski, Torsten Sacher
Journal of Virology. 2010
The phosphoproteome of toll‐like receptor‐activated macrophages
Gabriele Weintz, Jesper V Olsen, Katja Frühauf, Magdalena Niedzielska, Ido Amit, Jonathan Jantsch, Jörg Mages, Cornelie Frech, Lars Dölken, Matthias Mann, Roland Lang
Molecular Systems Biology. 2010
Dominant Negative Mutants of the Murine Cytomegalovirus M53 Gene Block Nuclear Egress and Inhibit Capsid Maturation
Mirela Popa, Zsolt Ruzsics, Mark Lötzerich, Lars Dölken, Christopher Buser, Paul Walther, Ulrich H. Koszinowski
Journal of Virology. 2010
Post-transcriptional regulation of miR-27 in murine cytomegalovirus infection
Amy H. Buck, Jonathan Perot, Michael A. Chisholm, Diwakar S. Kumar, Lee Tuddenham, Valérie Cognat, Lisa Marcinowski, Lars Dölken, Sébastien Pfeffer
RNA. 2010

2009

All for One and One for All: Herpesviral MicroRNAs Close in on Their Prey
Lars Dölken, Stipan Jonjic
Cell Host & Microbe. 2009
Metabolic tagging and purification of nascent RNA: implications for transcriptomics
Caroline C Friedel, Lars Dölken
Molecular BioSystems. 2009
Conserved principles of mammalian transcriptional regulation revealed by RNA half-life
Caroline C. Friedel, Lars Dölken, Zsolt Ruzsics, Ulrich H. Koszinowski, Ralf Zimmer
Nucleic Acids Research. 2009
Cytomegalovirus microRNAs
Lars Dölken, Sébastien Pfeffer, Ulrich H. Koszinowski
Virus Genes. 2009

2008

Age-Dependent Prevalence and Frequency of Circulating t(14;18)-Positive Cells in the Peripheral Blood of Healthy Individuals
G. Dolken, L. Dolken, C. Hirt, C. Fusch, C. S. Rabkin, F. Schuler
JNCI Monographs. 2008
High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay
Lars Dölken, Zsolt Ruzsics, Bernd Rädle, Caroline C. Friedel, Ralf Zimmer, Jörg Mages, Reinhard Hoffmann, Paul Dickinson, Thorsten Forster, Peter Ghazal, Ulrich H. Koszinowski
RNA. 2008
Small Noncoding RNA: Novel Targets for Antiviral Therapy
Lars Dölken, Jürgen Haas
Future Microbiology. 2008

2007

Mouse Cytomegalovirus MicroRNAs Dominate the Cellular Small RNA Profile during Lytic Infection and Show Features of Posttranscriptional Regulation
Lars Dölken, Jonathan Perot, Valérie Cognat, Abdelmalek Alioua, Matthias John, Jürgen Soutschek, Zsolt Ruzsics, Ulrich Koszinowski, Olivier Voinnet, Sébastien Pfeffer
Journal of Virology. 2007